Ithuba lethu lobuchwepheshe

Synthesis of chiral compounds, ultra-low temperature reactions, anhydrous and oxygen-free reactions, hydrogenation reactions, reduction alkylation, Friedel-alkyl/acyl reactions, substitution reactions

Patents: 50 i-patent zokwakha zifakwe, phakathi kwazo 30 zingamaphatent kazwelonke kanti 4 zingamaphatent aseMelika, njengokuthi: Indlela yokuhlanganisa i-rosulavatin calcium, indlela yokulungiselela i-4-(4-fluorophenyl) -6-isopropyl-2 -(n-methyl-n-methylsulfonylamino) pyrimidine-5-formaldehyde, indlela yokuhlanganisa i-(S) -2-amino-5-methoxy-1,2,3, 4-tetrahydronaphthalene hydrochloride, i-intermediate ye-silodoxin kanye nendlela yayo yokulungiselela Futhi indlela yokulungiselela i-silodoxin ngale intermediate

Ibhizinisi ikhiqiza ikakhulu ama-calcium intermediates e-rosuvastatin ne-pivastatin, okuyimidlaliso yokwehlisa ama-lipid. Ngaphezu kweminyaka eyishumi yokuhlangenwe nakho kokukhiqiza, ibhizinisi lidlula ezinsukwini eziningi zokuhlola ngonyaka. Ikhwalithi yomkhiqizo ihambisana nezindinganiso ze-USP, EP, JP kanye ne-CP, futhi imikhiqizo ithunyelwa kwamanye amazwe angaphezu kweshumi kuhlanganise ne-Japan, iNingizimu Korea ne-India. Ikakhulukazi ezimakethe ezincane ze-rosuvastatin calcium ne-renosine, linemithombo yokuthengisa ezinzile nezinsiza zamakhasimende aphezulu.